Marseille: Defender and Rolando will miss out due to a calf problem, meaning Luiz Gustavo is expected to fill in at centre-half. Meanwhile, striker Kostas Mitroglou is a doubt with a knock.
Atletico Madrid: Centre-back Jose Gimenez and winger Vitolo both face a race against time to prove their fitness due to ongoing muscular problems, but the club hopes the pair will both be available.
Marseille boss Rudi Garcia:
"We have a pretty small chance of winning but we are going to give it our all. Playing Atlético is a big event for us.
"This is a club who have played two Champions League finals in the past four years, a club that won the Europa League not long ago. But a final at home in France is a fantastic opportunity.
"No French side have ever won this trophy; it would be fantastic if we could be the first."
Atletico Madrid boss Diego Simeone:
"Everything is set up for a great final. [Marseille have] been improving and they have a coach who has so many options at his disposal and a lot of nous.
"They're very dangerous, particularly in midfield and attack. It'll certainly be a tough game. As soon as we got knocked out of the Champions League, we immediately embraced this competition.
"Being widely billed as contenders to reach the final heightened our sense of duty and responsibility. And here we are."
Did you know?
No French club has ever won the UEFA Cup or Europa League.
Marseille have won just one of their nine away games in this season's Europa League, compared to eight out of nine at the Stade Vélodrome.
This will be the second time Atletico have featured in a UEFA final in Lyon, having previously lost 3-0 to Dynamo Kiev in the 1986 European Cup Winners' Cup at the Stade de Gerland.
Form:
Possible lineups:
Marseille: Mandanda; Sakai, Rami, Luiz Gustavo, Amavi; Anguissa, Sanson; Thauvin, Payet, Ocampos; Germain.
Atletico Madrid: Oblak; Vrsaljko, Giménez, Godín, Lucas; Koke, Saúl Ñíguez, Gabi, Correa; Griezmann, Costa.