The game appeared to be heading towards a goalless draw as the clock moved into added time, but as they say, it only takes a second to score a goal.
With seconds remaining, Alex Sandro found Dybala on the edge of the box and the Argetine fired a low effort towards the near post.
Dybala for his part, struck the ball beautifully and had already began to wheel away in celebration when the outstretched right hand of Ter Stegen got down low to deny him.
They say a good goalkeeper wins you 10-15 points of the course of a season and Barca certainly had the German to thank for one on Wednesday.
Check out the save for yourself below:
How is this even possible Ter Stegen's reflexes are comparable to superheroes'!
— Diehard Cule (@TheBarcaAddict) 22 November 2017
pic.twitter.com/L6t0XRX1e4