Klopp believes Mauricio Pochettino has assembled such a strong squad at Spurs, that his only problem in the next few seasons will be keeping hold of his top players.
Liverpool currently sit in eighth position, four points behind third-placed Tottenham ahead of their trip to Wembley on the weekend, and the Klopp is anticipating an exciting encounter.
"It is a nice football game, I am looking forward to it," the German coach said on Friday. "Both teams don't hesitate with their effort.
"Tottenham did a bit better than us result-wise so far, but they can still play better and we can still play better.
"Fantastic development (from Tottenham) since I was in England. So far, apart from (Kyle) Walker this year, nobody left the club - that is a big job they have done so far.
"It will be a big challenge for them in the next few years because Harry is not only one of the best strikers in Europe, he is one of the best strikers in the world - 100 per cent.
"Everybody knows that, and Dele Alli as well, and (Christian) Eriksen as well. They are in a really good moment as a club."
Liverpool kept Romelu Lukaku fairly quiet during last week's 0-0 draw with Manchester United, but Klopp things Kane will pose different problems to his Belgian counterpart.
"I don't have to judge these two," he said. "They are both fantastic strikers.
"The difference is that Harry is much more a part of the game when he is not scoring - but I am pretty sure Lukaku can make these steps too.
"We avoided the balls to Lukaku and that must be a key for Harry as well but, if we are too concentrated on one player, then Dele Alli is everywhere or Eriksen shoots from everywhere with decisive passes."